Super-fast drug load of nanoparticle formulations
Quantify Payloads in LNPs in Seconds
UV/Vis spectroscopy is great for quantifying biological molecules in solution, but encapsulation in nanoparticles causes the light to scatter, which introduces big measurement errors.
Marama Labs' Scatter-Free Absorption (SFA) technology eliminates the interference caused by scattered light by design. This makes for accurate quantification of RNA and other encapsulated biomolecules without needing lysis to release the payload or fluorescent assays.
Scatter-Free Absorption
Our patented SFA technology enables simple and effective use of accepted UV quantification methods by measuring the absorption spectrum without the scatter that clouds regular UV/Vis analysis.
Scatter inherent in biological samples - nanoparticles, cells, bacteria, etc., is avoided without any a priori knowledge of the particle size or makeup.
CloudSpec cuts through cloudiness for rapid and easy quantification and particle characterisation.
CloudSpec - Scatter-Free Analysis in Seconds
CloudSpec cuts through scatter making UV/Vis measurements of cloudy samples as easy as, well, as easy as UV/Vis. If you want to quantify an analyte but couldn't because it was cloudy then CloudSpec is for you.
CloudSpec requires minimal sample prep - just a sample dilution - and a 15-second measurement, for fast, simple and precise sample analysis.
Scatter-Free Absorption
Our patented SFA technology enables simple and effective use of accepted UV quantification methods by measuring the absorption spectrum without the scatter that clouds regular UV/Vis analysis.
Scatter inherent in biological samples - nanoparticles, cells, bacteria, etc., is avoided without any a priori knowledge of the particle size or makeup.
CloudSpec cuts through cloudiness for rapid and easy quantification and particle characterisation.
Applications of CloudSpec
Just like regular UV/Vis, there are many applications for CloudSpec. If your sample scatters light, but you need a quantitative analysis in the UV or visible region, then CloudSpec will provide the answer.
Therapeutic particles <300nm in size, such as liposomes, LNPs, metal NPs, etc., are ideal as they scatter light significantly and are otherwise difficult to analyse non-destructively. Growth in bacteria and cells can be monitored to understand the underlying processes.
